Home | Shopping |Health A - Z | Supplements A - Z | Terms | Help | | Contact Us | Basket | Checkout
To Place an order, please call
Home Page
Carnosine Full Index
What is Carnosine?
Dr Kyriazis The Interview
Carnosine Book
News
References
Shopping
Shopping Pages
Special Offers
Search Shop

Carnosine (L-Carnosine)

Carnosine - Scientific References

  • High Strength Carnosine
     90 Caps x 500mg
    Was £49.99
    Now £29.99
    High Strength Carnosine

    Abe H. Role of Histidine-Related Compounds as Intracellular Proton Buffering Constituents in Vertebrate Muscle. Biochemistry (Mosc) 2000;65:7

  • Aerts L, Van Assche FA. Low taurine, gamma-aminobutyric acid and carnosine levels in plasma of diabetic pregnant rats: consequences for the offspring. J Perinat Med. 2001;29(1):81-4.(PubMed)

  • Alaghband-Zadeh J, Mehdizadeh S, Khan NS, et al. The natural substrate for nitric oxide synthase activity. Cell Biochem Funct. 2001;19(4):277-80. (PubMed)

  • Aldini G, Carini M, Beretta G, et al. Carnosine is a quencher of 4-hydroxy-nonenal: through what mechanism of reaction? Biochem Biophys Res Commun. 2002;298(5):699-706. (PubMed)

  • Baran EJ. Metal complexes of carnosine. Biochemistry (Mosc) 2000;65(7):789-97 (PubMed) [Click "Go to publisher´s site" for full text]

  • Baslow MH. Function of the N-acetyl-L-histidine system in the vertebrate eye. Evidence in support of a role as a molecular water pump. J Mol Neurosci, 1998, 10(3), 193-208.

  • Baslow MH, Suckow RF, Berg MJ et al. Differential expression of carnosine, homocarnosine and N-acetyl-L-histidine hydrolytic activities in cultured rat macroglial cells. J Mol Neurosci. 2001 Dec;17(3):351-9. (PubMed)

  • Baynes JW, Thorpe SR. Role of oxidative stress in diabetic complications: a new perspective on an old paradigm. Diabetes 1999;48 (1) 1-9,

  • Bharadwaj LA, Davies GF, Xavier IJ et al. l-carnosine and verapamil inhibit hypoxia-induced expression of hypoxia inducible factor (HIF- 1 alpha) in H9c2 cardiomyoblasts. Pharmacol Res. 2002 Mar;45(3):175-181.(PubMed)

  • Boldyrev AA. Problems and Perspectives in Studying the Biological Role of Carnosine. Biochemistry (Mosc) 2000;65:7

  • Boldyrev A. Carnosine as a modulator of endogenous Zn(2+) effects. Trends Pharmacol Sci. 2001;22(3):112-3.(PubMed)

  • Boldyrev AA, Gallant SC, Suhkich GT. Carnosine, the protective, anti-aging peptide. Biosci Rep, 1999, 19 (6), 581-7.(PubMed)

  • Boldyrev AA, Yuneva MO, Sorokina EV et al. Antioxidant systems in tissues of senescence accelerated mice. Biochemistry (Mosc). 2001;66(10):1157-63. (PubMed) [Click "Go to publisher´s site" for full text]

  • Bonfanti L, Peretto P, De Marchis S et al. Carnosine-related dipeptides in the mammalian brain. Prog Neurobiol. 1999 Nov;59(4):333-53. Review. (PubMed)

  • Brownson C, Hipkiss AR. Carnosine reacts with a glycated protein. Free Radic Biol Med. 2000 May 15;28(10):1564-70. (PubMed)

  • Chace KV, Carubelli R, Nordquist RE. The role of nonenzymatic glycosylation, transition metals, and free radicals in the formation of collagen aggregates. Arch Biochem Biophys 1991;288(2):473-80 (PubMed)

  • Chen Y, Ho CT. Effects of carnosine on volatile generation from Maillard reaction of ribose and cysteine. J Agric Food Chem. 2002;50(8):2372-6. (PubMed)

  • Chez MG, Buchanan CP, Komen JL, Becker M. Double-blind, placebo-controlled study of L-carnosine supplementation in children with autistic spectrum disorder. Journal of Child Neurology 2003 (accepted for publicationt). (Abstract)

  • Decker EA, Livisay SA, Zhou S. Re-evaluation of the Antioxidant Activity of Purified Carnosine. Review. Biochemistry (Mosc) 2000;65:7

  • High Strength Carnosine
     90 Caps x 500mg
    Was £49.99
    Now £29.99
    High Strength Carnosine

    Decker EA, Ivanov V, Zhu BZ, Frei B. Inhibition of low-density lipoprotein oxidation by carnosine histidine. J Agric Food Chem. 2001 Jan;49(1):511-6. (PubMed)

  • Dukic-Stefanovic S, Schinzel R, Riederer P, Munch G. AGES in brain ageing: AGE-inhibitors as neuroprotective and anti-dementia drugs? Biogerontology. 2001;2(1):19-34. Review. (PubMed)

  • Dunnett M, Harris RC, Dunnett CE, Harris PA. Plasma carnosine concentration: diurnal variation and effects of age, exercise and muscle damage. Equine Vet J Suppl. 2002;(34):283-7. (PubMed)

  • Ferraris R. P., Diamond J., Kwan W. W. Dietary regulation of intestinal transport of the dipeptide carnosine. Am. J. Physiol. 1988;255:G143-G150 (PubMed)

  • Gallant S, Semyonova M, Yuneva M. Carnosine as a potential anti-senescence drug. Biochemistry (Mosc). 2000l;65(7):866-8.(PubMed) [Click "Go to publisher´s site" for full text]

  • Gallant S, Kukley M, Stvolinsky S et al. Effect of carnosine on rats under experimental brain ischemia. Tohoku J Exp Med. 2000 Jun;191(2):85-99.(PubMed)

  • Gariballa SE, Sinclair, AJ. Carnosine: physiological properties and therapeutic potential. Age and Aging, 2000, 29: 207-210..(PubMed)

  • Halliwell B.Gutteridge, JMC. (1999) Free Radicals in Biology and Medicine, Oxford University Press, Oxford- N. Y.

  • Hayflick L. The limited in vitro lifetime of human diploid cell strains. Exp Cell Res. 1965; 37:614-36.

  • Hayflick L, Moorhead PS. The serial cultivation of human diploid cell strains. Exp Cell Res. 1961; 25:585-621.

  • Hipkiss AR. Could carnosine be a naturally-occurring scavenger for acrolein and other reactive aldehydes in the brain? Neurobiol Aging. 2002;23(4):645-6. (PubMed)

  • Hipkiss AR, Brownson C, Bertani MFReaction of carnosine with aged proteins: another protective process? Ann N Y Acad Sci. 2002;959:285-94. Review. (PubMed)

  • Hipkiss AR, Brownson C. A possible new role for the anti-aging peptide carnosine. Cell Mol Life Sci, 2000 a., 57 (5): 747-53. (PubMed)

  • Hipkiss AR, Brownson C. Carnosine reacts with protein carbonyl groups: another possible role for the anti-ageing peptide? Biogerontology. 2000 b;1(3):217-23. Review. (PubMed)

  • Hipkiss AR, Brownson C, Carrier MJ. Carnosine, the anti-ageing, anti-oxidant dipeptide, may react with protein carbonyl groups. Mech Ageing Dev. 2001 Sep 15;122(13):1431-45. (PubMed)

  • Hipkiss AR. Biosynthesis, Release, and Uptake of Carnosine in Primary Cultures. Review. Biochemistry (Mosc) 2000 c;65:7

  • Hipkiss AR. et al. Protective effects of carnosine against MDA-induced toxicity towards cultured rat brain endothelial cells. Neuroscience Letters. 1997. 135-138.

  • Hipkiss AR et al. Protective effects of carnosine against protein modification mediated by nialondialdchyde and hypochlorite. Bioch Biophys Acta 1998, 1380;46- 54.

  • Hollyday R, McFarland GA. A Role for Carnosine in Cellular Maintenance. Review Biochemistry (Mosc) 2000;65:7

  • Horning MS, Blakemore LJ, Trombley PQ. Endogenous mechanisms of neuroprotection: role of zinc, copper, and carnosine. Brain Res. 2000;852(1):56-61.(PubMed)

  • Jackson MC, Lenney JF. The distribution of carnosine and related dipeptides in rat and human tissues. Inflamm Res 1996, 45(3): 132-5.

  • Jin M, Otaka M, Watanabe S. [New therapeutic approaches to peptic ulcer using mucosal protective agents] Nippon Rinsho. 2002;60 Suppl 2:377-81. Review.

  • Kang JH, Eum WS. Enhanced oxidative damage by the familial amyotrophic lateral sclerosis-associated Cu,Zn- superoxide dismutase mutants. Biochim Biophys Acta. 2000 Dec 15;1524(2-3):162-70. (PubMed)

  • Kang JH, Kim KS, Choi SY et al. Carnosine and related dipeptides protect human ceruloplasmin against peroxyl radical-mediated modification. Mol Cells. 2002;13(3):498-502.

  • High Strength Carnosine
     90 Caps x 500mg
    Was £49.99
    Now £29.99
    High Strength Carnosine

    Kang KS, Yun JW, Lee YS. Protective effect of L-carnosine against 12-O-tetradecanoylphorbol-13-acetate- or hydrogen peroxide-induced apoptosis on v-myc transformed rat liver epithelial cells. Cancer Lett. 2002 Apr 8;178(1):53-62. (PubMed)

  • Kang JH, Kim KS, Choi SY et al. Protection by carnosine-related dipeptides against hydrogen peroxide-mediated ceruloplasmin modification. Mol Cells. 2002 a.;13(1):107-12.(PubMed)

  • Keane F, O'Cuinn G. Two broad-specificity dipeptide hydrolysing activities from cytoplasm of guinea pig brain, both of which contain prolinase but neither of which contain carnosinase activity. Neurosci Res. 2002 b.;44(1):111-20. (PubMed)

  • Khaspekov LG, Klyushnik TP, Dupin AM, Lyzhin AA, Bezrukov MV. Protective effect of Biolan during ischemic damages to cultured cerebellar granular cells. Bull Exp Biol Med. 2002;133(2):136-8. (PubMed)

  • Kynazis M. 1999. Data on file.

  • Lovell MA, Xie C, Markesbery WR. Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal cultures. Neurobiol Aging 2001;22(2):187-94 (PubMed)

  • MacFarlane N, McMurray J, O'Dowd JJ, Dargie HJ, Miller DJ. Related Articles, Links Synergism of histidyl dipeptides as antioxidants. J Mol Cell Cardiol. 1991;23(11):1205-7. (PubMed)

  • Maichuk UF, Formaziuk VE, Sergienko VI. Development of carnosine eyedrops and assessing their efficacy in corneal diseases. Vestn Oftalmol, 1997, 113(6): 27- 31.

  • Maynard LM, Boissonneault GA, Chow CK, Bruckner GG. High levels of dietary carnosine are associated with increased concentrations of carnosine and histidine in rat soleus muscle. J Nutr. 2001;131(2):287-90. (PubMed) Click in the absrtact for Free full text.

  • Marchis SD, Modena C, Peretto P et al. Carnosine-related dipeptides in neurons and glia. Biochemistry (Mosc). 2000;65(7):824-33. (PubMed) [Click "Go to publisher´s site" for full text]

  • Margolis FL. Carnosine in the primary olfactory pathway. Science. 1974;184(139):909-11

  • McFarland GA, Holliday R. Retardation of the senescence of cultured human diploid fibroblasts by carnosine. Exp Cell Res, 1994, 212(2): 167-75.

  • McFarlandGA ,Holliday R. Further evidence for the rejuvenating effects of the dipeptide I L--carnosine on cultured human diploid fibroblast. Exp Gerontol 1999 34(l):35-45.

  • Nagai K, Suda T, Kawasaki K, Yamaguchi Y. Effects of L-carnosine on blood cells and biomembrane. Nippon Seirigaku Zasshi, 1990, 52(10): 339-44.

  • Nagai K, Suda T. Immuno-enhancing actions of carnosine and homocarnosine. Nippon Seirigaku Zasshi, 1986, 48 (11):735-40.

  • Nagai K, Suda T; Realization of spontaneous healing function by carnosine. Methods Find Exp Clin Pharmocol, 1988, 10(8): 497-507.

  • Nagasawa T, Yonekura T, Nishizawa N, Kitts DD. In vitro and in vivo inhibition of muscle lipid and protein oxidation by carnosine. Mol Cell Biochem. 2001;225(1-):29-34.(PubMed)

  • Nguimfack Mbodie PC. [Do the glutamate excitotoxicity theory and potential free radicals implication in schizophrenia aetiopathogenesis provide a new enlightenment to links between: genome, environment and biology in the determinism of that disorder?] Encephale. 2002;28(2):147-53. (PubMed)

  • Niijima A, Okui T, Matsumura Y, Yamano T, et al.Effects of L-carnosine on renal sympathetic nerve activity and DOCA-salt hypertension in rats. Auton Neurosci. 2002;97(2):99-102. (PubMed)

  • Nikitenko Niu, Shavratskii VKh, Boldyrev AA et al. Effect of carnosine and its derivatives on ADP-induced human platelet aggregation. Vopr Med Khim, 1995, 41(1): 41-3.

  • O'Dowd JJ, Robins DJ, Miller DJ. Detection, characterisation, and quantification of carnosine and other histidyl derivatives in cardiac and skeletal muscle. Biochim Biophys Acta. 1988;967(2):241-9. (PubMed)

  • Peretto P, Luzzati F, Bonfanti L et al. Aminoacyl-histidine dipeptides in the glial cells of the adult rabbit forebrain. Peptides. 2000;21(11):1717-24.(PubMed)

  • Petroff OA, Hyder F, Rothman DL, Mattson RH Homocarnosine and seizure control in juvenile myoclonic epilepsy and complex partial seizures. Neurology. 2001;56(6):709-15.(PubMed)

  • Petroff OA, Hyder F, Rothman DL et al. Effects of gabapentin on brain GABA, homocarnosine, and pyrrolidinone in epilepsy patients. Epilepsia. 2000;41(6):675-80 (PubMed)

  • Preston J et al. Toxic effects of B-amyloid on immortalised rat brain endothelial cell: protection by carnosine, homocarnosine and B-alanine. Neuroscience letters 1998, 242; 105-108.

  • Quinn PL Boldyrev AA. Formaziuk VH. Carnosine: its properties, functions and potential therapeutic applications. Mol Aspects Mod, 1992, 13(5):379-444.

  • Price DL, Rhett PM, Thorpe SR, et al. Chelating activity of advanced glycation end-product inhibitors. J Biol Chem. 2001;276(52):48967-72. [Full text]

  • Ririe DG, Roberts PR, Shouse MN, Zaloga GP. Vasodilatory actions of the dietary peptide carnosine. Nutrition. 2000 Mar;16(3):168-72. (PubMed)

  • Roberts PR, Black KW, Santamauro JT. Dietary peptides improve wound healing following surgery. Nutrition, 1998, 14(3):266-9. (PubMed)

  • Roberts PR, Zaloga GP. Cardiovascular effects of carnosine. Biochemistry (Mosc). 2000 Jul;65(7):856-61. Review. (PubMed) [Click "Go to publisher´s site" for full text]

  • Rubtsov AM. Molecular mechanisms of regulation of the activity of sarcoplasmic reticulum Ca-release channels (ryanodine receptors), muscle fatigue, and Severin's phenomenon. Biochemistry (Mosc). 2001 Oct;66(10):1132-43. Review. (PubMed) [Click "Go to publisher´s site" for full text]

  • High Strength Carnosine
     90 Caps x 500mg
    Was £49.99
    Now £29.99
    High Strength Carnosine

    Sankarasubbaiyan S, Cooper C, Heilig CW. Identification of a novel form of renal glucosuria with overexcretion of arginine, carnosine, and taurine. Am J Kidney Dis. 2001;37(5):1039-43. (PubMed)

  • Seidler NW, Yeargans GS. Effects of thermal denaturation on protein glycation. Life Sci. 2002 ;70(15):1789-99. (PubMed)

  • Severina IS, Bussygina OG, Pyatakova NV. Carnosine as a Regulator of Soluble Guanylate Cyclase. Review. Biochemistry (Mosc) 2000;65:7

  • Skulachev VP. Problems and Perspectives in Studying the Biological Role of Carnosine (Introduction of the Guest-Editor) Biochemistry (Mosc) 2000;65:7

  • Smythies J. Redox mechanisms at the glutamate synapse and their significance: a review. Eur J Pharmacol. 1999;370(1):1-7. Review. (PubMed)

  • Soliman K, El-Ansary A, Mohamed AM. Effect of carnosine administration on metabolic parameters in bilharzia-infected hamsters. Comp Biochem Physiol B Biochem Mol Biol. 2001;129(1):157-64. (PubMed)

  • Stadtman ER, Levine RL.Protein Oxidation Ann. N.Y. Acad. Sci. 2000; 899(1): 191 - 208. (Abstract)

  • Steinberg C, Notterman DA. Hemodynamic effects of carcinine in the anesthetized, instrumented, open-chest rat. Crit Care Med. 1996;24(12):2042-5.(PubMed)

  • Stuerenburg HJ. The roles of carnosine in aging of skeletal muscle and in neuromuscular diseases. Biochemistry (Mosc). 2000l;65(7):862-5. Review.(PubMed) [Click "Go to publisher´s site" for full text]

  • Stuerenburg HJ, Kunze K; Concentrations of free carnosine (a putative membrane- protective antioxidant) in human muscle Biopsies and rat muscles. Archives of Gerontology and Geriatrics, 1999, 29: 107-113.

  • Stvolinsky SL, Dobrota D. Anti-ischemic activity of carnosine. Biochemistry (Mosc). 2000;65(7):849-55. Review. (PubMed) [Click "Go to publisher´s site" for full text]

  • Stvolinsky S, Kukley M, Dobrota D. Carnosine protects rats under global ischemia. Brain Res Bull. 2000;53(4):445-8.(PubMed)

  • Sunderman FW Jr. Nasal toxicity, carcinogenicity, and olfactory uptake of metals. Ann Clin Lab Sci. 2001;31(1):3-24. Review. (PubMed)

  • Suslina ZA, Federova TN, Maksimova MIu et al. [Antioxidant therapy in ischemic stroke] Zh Nevrol Psikhiatr Im S S Korsakova. 2000;100(10):34-8 (PubMed)

  • Suzuki Y, Ito O, Mukai N, Takahashi H, Takamatsu K. High Level of Skeletal Muscle Carnosine Contributes to the Latter Half of Exercise Performance during 30-s Maximal Cycle Ergometer Sprinting. Jpn J Physiol. 2002;52(2):199-205. (PubMed)

  • Tabakman R, Lazarovici P, Kohen R. Neuroprotective effects of carnosine and homocarnosine on pheochromocytoma PC12 cells exposed to ischemia. J Neurosci Res. 2002;68(4):463-9. (PubMed)

  • Tameyasu T, Yamada M, Tanaka M, Takahashi S. Effect of zinc-carnosine chelate compound on muscle function in mdx mouse. Jpn J Physiol. 2002;52(1):111-20. (PubMed)

  • Tan KM, Candlish JK. Carnosine and anserine as modulators of neutrophil function. Clin Lab Haematol, 1998, 20(4): 239-44.

  • Tarnha M, et al. Hydroxyl radical scavenging by carnosine and Cu(ii)-carm)sine complexes. Int J Radial Biol, 1999 75(9):1 177-1188.

  • Thorpe SR, Baynes JW. Role of the Maillard reaction in diabetes mellitus and diseases of aging. Drugs Aging 1996;9(2):69-77 (PubMed)

  • Trombley PQ, Horning MS, Blakemore LJ. Interactions between carnosine and zinc and copper: implications for neuromodulation and neuroprotection. Biochemistry (Mosc). 2000 Jul;65(7):807-16. Review. (PubMed) [Click "Go to publisher´s site" for full text]

  • High Strength Carnosine
     90 Caps x 500mg
    Was £49.99
    Now £29.99
    High Strength Carnosine

    Truitsina IE, Shabanov M, Chikunova BZ, et al.Characterization of the anti-ulcer effectiveness of carnosine. Patol Fiziol Eksp Ter, 1997, 4: 17-20.

  • Yamano T, Niijima A, Iimori S, et al. Effect of L-carnosine on the hyperglycemia caused by intracranial injection of 2-deoxy-D- glucose in rats. Neurosci Lett. 2001;313(1-2):78-82. (PubMed)

  • Yuneva MO, Bulygina ER, Gallant SC et al. Effect of carnosine on age- induced changes in senescence-accelerated mice. J Anti-Aging Medicine, 2: 1999, 337-342. (PubMed)

  • Zaloga GP, Roberts PR, Black KW. et al. Carnosine is a novel peptide modulator of intracellular calcium and contractility in cardiac cells. Am J Physiol. 1997;272(1 Pt 2):H462-8. (PubMed)

  • Further references at PubMed, search for ´carnosine´.

Download Carnosine Product Brochure ()
Home| About| Terms| Site Map| Help| Contact Us| | Shopping
 
First Vitality International Ltd
 
Copyright © 2001 - 2008 1st Vitality. All rights reserved.
Please review the Terms of Use before using this site. Your use of the site indicates your agreement to be bound by the Terms of Use.